Abstract
There are no published reports that include both timely antemortem and postmortem carbamazepine concentrations after massive overdose. We report a fatal overdose of carbamazepine with both timely antemortem and postmortem carbamazepine concentrations. Carbamazepine concentrations were 47.7 mcg/mL 2 h antemortem and 53 mcg/mL at 9 h postmortem. The slight rise in drug concentration may reflect continued absorption of the drug in the last 2 h before death. Postmortem carbamazepine concentrations drawn from a peripheral vessel in this patient appeared to reflect drug concentrations at the time of death.
Keywords:
carbamazepine, drug concentrations, forensic science, overdose, postmortem
Paper ID: JFS4661510
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Author Spiller HA, Carlisle RD
Title Timely antemortem and postmortem concentrations in a fatal carbamazepine overdose
Symposium ,
Committee on
