Distribution of types for six PCR-based loci, LDLR, GYPA, HBGG, D7S8, GC and HLA-DQA1 in central Pyrenees and Teruel (Spain)
Bell, B
Research scientists and professor of the Department of Legal Medicine,University of Zaragoza, Zaragoza, Spain.

Budowle, B
Unit chief, Forensic Science Research and Training Center, FBI Academy,Quantico, VA.

Martinez-Jarreta, B
Research scientists and professor of the Department of Legal Medicine,University of Zaragoza, Zaragoza, Spain.

Casalod, Y
Research scientists and professor of the Department of Legal Medicine,University of Zaragoza, Zaragoza, Spain.

Abecia, E
Research scientists and professor of the Department of Legal Medicine,University of Zaragoza, Zaragoza, Spain.

Castellano, M
Research scientists and professor of the Department of Legal Medicine,University of Zaragoza, Zaragoza, Spain.


Abstract
The PCR-based DNA loci LDLR, GYPA, HBGG, D7S8, GC and HLA DQA1 are widely used in forensic casework analyses. Population data on the distribution of allele frequencies are desired to estimate the rarity of a DNA profile. We studied the allele distributions at these forensically important DNA markers in two Spanish populations (Central Pyrenees and Teruel). Results were in agreement with Hardy-Weinberg expectations. Furthermore, there was little evidence for departures from expectation of independence between loci within the two sample populations. Tests for homogeneity were carried out between the two Spanish populations and a U.S. Caucasian population.

Keywords:
Central Pyrenees, D7S8, DNA, DNA typing, forensic science, GC, genetic typing, GYPA, HBGG, HLA-DQA1, LDLR, pathology and biology, population genetics, populations, Spain, Teruel

Paper ID: JFS423970510

ASTM International is a member of CrossRef.
Author Bell B, Budowle B, Martinez-Jarreta B, Casalod Y, Abecia E, Castellano M Title Distribution of types for six PCR-based loci, LDLR, GYPA, HBGG, D7S8, GC and HLA-DQA1 in central Pyrenees and Teruel (Spain) Symposium , Committee on