Greek Cypriot allele and genotype frequencies for Amplitype® PM-DQA1 and D1S80 loci
Cariolou, MA
Director, DNA ID Lab, biologist, visiting student, molecular biologist, respectively, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia, Cyprus.

Manoli, P
Director, DNA ID Lab, biologist, visiting student, molecular biologist, respectively, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia, Cyprus.

Christophorou, M
Director, DNA ID Lab, biologist, visiting student, molecular biologist, respectively, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia, Cyprus.

Bashiardes, E
Director, DNA ID Lab, biologist, visiting student, molecular biologist, respectively, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia, Cyprus.

Karagrigoriou, A
Associate professor, Department of Mathematics and Statistics, University of Cyprus, Nicosia, Cyprus.

Budowle, B
Unit Chief, Forensic Science Research and Training Center, FBI Academy, Quantico, VA.


Abstract
A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.

Keywords:
Cyprus, D1S80, D7S8, DNA typing, forensic science, GC, GYPA, HBGG, HLA-DQA1, LDLR, polymerase chain reaction, polymerase chain reaction (PCR), population genetics

Paper ID: CH30661X

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Author Cariolou MA, Manoli P, Christophorou M, Bashiardes E, Karagrigoriou A, Budowle B Title Greek Cypriot allele and genotype frequencies for Amplitype® PM-DQA1 and D1S80 loci Symposium , Committee on