Some Effects of Mechanical Trauma on the Development of Primary Cancers and Their Metastases
Weiss, L
Chief cancer research clinician, Department of Experimental Pathology, Roswell Park Memorial Institute, Buffalo, NY.


Abstract
Posttraumatic inflammation and, much less commonly, mechanical trauma itself may affect the clinical course of cancer. There is no evidence that a single incident of trauma can cause cancer, although posttraumatic chronic inflammation may be associated with carcinogenesis. In patients with cancer at the time of trauma, inflammation and repair processes may inhibit or enhance cancer growth, and trauma and its sequelae may increase the rates of invasion and dissemination.

Keywords:
cancer, carcinogenesis, forensic science, injuries, invasion, mechanical trauma, metastasis, pathology and biology, polyethylene glycol

Paper ID: JFS353900614

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Author Weiss L Title Some Effects of Mechanical Trauma on the Development of Primary Cancers and Their Metastases Symposium , Committee on